What Are the Main Differences Between Total Triterpenes and Madecassoside Series?

When formulating Centella Asiatica skincare, choosing between total triterpenes and madecassoside series can determine product efficacy by up to 40%. These extracts differ fundamentally in composition and applications. Total triterpenes contain all active compounds (asiaticoside, madecassoside, and their aglycones), while madecassoside series focus solely on the wound-healing compound madecassoside at 80-95% purity.

Why Is Centella Asiatica Extract Considered Effective for Sensitive Skin Care?

Clinical studies show 0.2% Centella extract reduces redness by 61% in 28 days, making it indispensable for sensitive skin formulations. Centella works through:

• ✓Anti-inflammatory triterpenes (inhibit IL-1 by 60%)
• ✓Barrier repair (stimulates ceramide production)
• ✓Microcirculation improvement (reduces erythema)

Key Mechanisms:

Data from in vivo studies

How Does Centella Asiatica Extract Promote Collagen Synthesis in Skincare?

Centella's triterpenes boost Type I/III collagen production by 150% compared to retinol, without irritation. The mechanism involves:

1. Fibroblast activation: +61% cell migration
2. MMP-1 inhibition: -72% collagen destruction
3. ECM protection: Strengthens dermal structure

Collagen Enhancement Comparison:

Based on dermatological studies

How to Source High-Quality Centella Asiatica Extract for Skincare Products?

75% of "Centella extracts" fail purity tests - these sourcing criteria separate premium actives from counterfeits. Demand:

• HPLC-certified purity (≥80% for total triterpenes)
• Solubility documentation (water/alcohol)

Supplier Evaluation Table:

Industry quality benchmarks

Conclusion

Total triterpenes offer broad-spectrum benefits (anti-inflammatory+anti-aging), while madecassoside series provide targeted wound healing. Verify purity, origin, and solubility when sourcing.